Everything about Viagra

Your mailbox is full every day with offers to buy the blue miracle pill online. You hear about it everywhere, but what exactly is the Viagra® pill? In this article we will tell you all about it.

WHAT IS VIAGRA®?

The company Pfizer launched Viagra® in 1998 and since then more than 27 million people have had a successful erection again thanks to the blue pill. It is actually Sildenafil, a pill that stimulates erection in men. The drug was patented in 1996, but it was not until 1998 that it was approved as an erection aid on the American market. Sildenafil became a huge success. Annual sales of Viagra® exceed $1 billion. The press said that Peter Dunn and Albert Wood were the inventors of the drug, but manufacturer Pfizer contradicts this. Their names are on the patent, but that’s about it. Pfizer still has a worldwide patent on Sildenafil that only expires in the period 2011-2013. Sildenafil has gained another important application in recent years. The drug is also able to lower the blood pressure of the pulmonary circulation. High blood pressure there is a life-threatening condition that was virtually untreatable until recently.

There are the wildest stories going around about Viagra®. One claims that it is a super potency pill and another compares the blue pill to a ‘love drug’. There are even those who claim that women benefit from it even more than men. Sildenafil was actually developed to treat angina (chest pain). However, during clinical tests it was found that the product had a stimulating effect on erection. Actually, it was discovered by chance, just like penicillin. Viagra ® or Sildenafil also enjoys worldwide fame through the Internet. This is mainly because Viagra® and many imitations are frequently offered via spam emails.

HAVE YOU RECEIVED SPAM CONCERNING VIAGRA® ???

Pfizer, the manufacturer of Viagra® emphasizes that it absolutely NEVER sends unsolicited emails about Viagra®. The best thing you can do if you receive such an unsolicited email about Viagra® is to delete the message without responding to it. No matter how reliable the email may look, keep in mind that there is a good chance that if you accept the offer you will not receive real Sildenafil or Viagra®, but a counterfeit or an inferior product that can even be dangerous to your health.

WHAT IS VIAGRA® NOT?

It is an absolute myth that Viagra® increases sex drive. That’s not true at all. Viagra ® does not make you romantic and certainly not horny either. Sildenafil is not an aphrodisiac. The product is therefore not a potency pill, but a medicine with which you can solve erection problems. By taking it you can get an erection again as before the erection problems, but you must ensure that you are sexually aroused. Otherwise IT WILL NOT WORK!!! Viagra® is certainly NOT a miracle drug for long-term uninhibited sex with an unprecedented erection that porn actor John Holmes would have envied. Viagra® is effective 4 to 5 hours after taking it. However, that does not mean that you will simply get an erection that lasts five hours. If sexual stimulation disappears or after an orgasm, the erection will also decrease and disappear. As far as is known and after various studies, Viagra® DOES NOT work in women. A woman’s sexual organ is completely different and their sexual problems are also of a completely different nature. So there is no point in giving your wife or girlfriend Viagra ® because nothing will happen. As far as we know, it is not harmful to administer Sildenafil to women, but it is a waste of money and completely pointless.

HOW DOES VIAGRA® WORK?

When an erection occurs, this is because the blood vessels in the penis relax. This allows these blood vessels to fill with blood. With erectile dysfunction, that part disappears. Viagra® ensures that the blood vessels can fill with blood again when aroused, so that that good old stiff friend is back in all its glory.

You should take the pill about one hour before sexual activity. In most cases it works within 30 to 60 minutes. In men who received Viagra ® during medical trials, the time to onset of an erection sufficient for sex was on average 25 minutes. It was between 12 and 37 minutes. It depends from person to person. It may take longer if you have eaten heavily or drank a lot of alcohol. Try to avoid drinking alcohol before taking Viagra ® as it will largely or even completely destroy the effect. Do not take more than the prescribed dose per day. Consult your doctor if Viagra® does not give the expected results. Viagra® works for 4 out of 5 men, but it is not certain that it will give a ‘satisfactory’ result the first time. Stress and fear of failure, just like in men who do not use or need Viagra ®, can lead to an inability to achieve an erection sufficient for sex. It is an absolute misunderstanding that the effect of Viagra® only starts 1 hour after taking the pill.

WHAT DOES VIAGRA® COST AND HOW MUCH CAN I TAKE?

Viagra® is ONLY available with a doctor’s prescription. Because so many men have problems with impotence or erection problems, it is very often prescribed. Your doctor will not be surprised or laugh at you if you ask. Viagra® is available in doses of 25mg, 50mg or 100mg. It is recommended to start with a dose of 50mg. You can then increase or decrease the dose if necessary. Once again you are dealing with a medication, so ALWAYS consult your doctor before using Viagra®. Always take one full pill. After all, the active component is not homogeneously distributed over the tablet, so in most cases taking half a pill will make no difference compared to a full pill, or even simply give little or no results. The price of real Viagra® is between 8 and 10 per piece, depending on the strength and the quantity you purchase. If someone wants to sell you Viagra ® cheaper somewhere, you are probably dealing with counterfeit.

There are also two other similar products on the market. Called Levitra and Cialis. It is not yet possible to say which of the three gives the best results. No comparative research has yet been done. Until further notice, the first choice remains Viagra®. Based on the ultimate effect or a possible side effect, you can make a different choice TOGETHER WITH YOUR DOCTOR. The effect of Cialis is much longer than Viagra® or Levitra. The disadvantage, however, is that the side effects last longer!!! If you suffer from blurred vision with Viagra®, there is a chance that this will be somewhat less with Levitra. The eye contains an abnormal enzyme PDE6. Levitra has a 30 times lower effect on PDE6 than Viagra®. This is the theory because in practice it remains to be proven whether these differences are effective.

LEVITRA

Levitra (vardenafil) comes in tablets of 5mg, 10mg and 20mg. The pill should be taken 30 minutes to one hour before sexual intercourse. The maximum dose is 20mg per day. If the drug is taken with a fatty meal, absorption can be delayed and the time for the product to work can even be doubled. After 4½ hours, half has already been excreted and the effect of the pill diminishes.

CIALIS

Cialis (tadalafil) works much longer than Viagra® or Levitra. The pill can be taken from one hour to 12 hours before sexual intercourse. Only after 18 hours is half of the substance excreted again. This has the advantage that you do not have to take into account how long the pill will remain effective. If it doesn’t work in the evening, that’s not a problem, you can try again in the morning without having to take a new pill. There are two strengths 10mg and 20mg. The price of both tablets is approximately the same as that of 10mg Levitra or 50mg Viagra®.

However, we will not delve deeper into these two other products for the time being, we will stick to the original Viagra® from Pfizer for this article.

WHEN SHOULD YOU NOT USE VIAGRA®?

You should ABSOLUTELY NOT use Viagra® if you are taking other medicines containing nitrate or nitrite. Nitrate is usually found in medicines for angina pectoris (chest pain). Nitrite is found in amyl nitrite (poppers). Viagra® can greatly enhance the effects of these specific drugs. If you are prescribed a new medicine, be sure to tell your doctor that you are also taking Viagra®. You should also not use Viagra® if you have ever had an allergic reaction after using Viagra® or one of the excipients (your pharmacist or GP knows which excipients Viagra® contains). These allergic reactions can include a rash, itching, a swollen face, swollen lips or shortness of breath. If you have ever experienced this after taking Viagra®, be sure to tell your doctor. Furthermore, you should not use Viagra® if you:

  • Have a serious heart problem.
  • Have recently had a stroke or heart attack.
  • You have the extremely rare eye disorder retinitis pigmentosa.
  • Your doctor has advised you against sexual activity.

You should also be careful when using Viagra® if you suffer from:

  • Sickle cell anemia (an abnormality of the red blood cells).
  • Leukemia (blood cell cancer).
  • Multiple myeloma (bone marrow cancer).
  • Have a stomach ulcer.
  • You are a hemophiliac or have another blood disorder.
  • Have other diseases of your penis or deformities.

If you have any doubts about the above, ALWAYS consult your doctor. You should also consult with your doctor if you develop kidney or liver problems over time. Your doctor may then decide to prescribe a different dose of the product. You should certainly not use Viagra® together with other treatments for erectile dysfunction unless approved by your doctor. It is a myth that you should never use Viagra® if you have heart and/or vascular disease. During the consultation, your doctor should carefully check whether your heart can handle the extra strain of sexual activity. In principle, this will not even be a danger to heart patients. Sexual activity with a steady partner is comparable in terms of physical exertion to normal daily activities such as gardening, golfing and washing the car.

WHAT ARE THE POSSIBLE SIDE EFFECTS OF VIAGRA®?

Viagra® can sometimes (depending on the person) cause side effects. These are usually mild to moderate and short-lived. The most common side effects are headache and flushing. Less commonly reported side effects include stomach upset, dizziness, a stuffy nose, a colored blur in front of the eyes, increased sensitivity to light or blurred vision. It is therefore advisable to always consider how you personally respond to Viagra® before driving a car or operating a machine. If you experience side effects not listed here, tell your doctor or pharmacist.

PLEASE NOTE: If you take more tablets or a higher dose than your doctor has prescribed, the effectiveness of Viagra® will not increase further. However, you WILL get more side effects and the side effects may be more serious. If you have taken more tablets than prescribed, inform your doctor.

Research showed that one in five people thinks that Viagra ® causes the penis to remain stiff for an annoyingly long time. The so-called priapism can be a side effect in very exceptional cases, but otherwise this is a major misunderstanding, just as we repeat that sexual stimulation is absolutely necessary to achieve the desired result.

VIAGRA® PRODUCT DETAILS

PHARMACEUTICAL DATA

  • Bioavailability: 40%
  • Metabolism: Liver (CYP2C9)
  • Half-life: 4 hours

USAGE

  • Drug group: Drugs for impotence
  • Subclass: Phosphodiesterase type 5 inhibitors
  • Brand Names: Viagra (Pfizer)
  • Indications: Erectile dysfunction
  • Prescription required: Yes
  • Administration: Oral

DATABASE DATA

  • CAS number: 171599-83-0
  • ATC code: BE03
  • PubChem: 5281023
  • Drug Bank: APRD00556

CHEMICAL DATA

  • Formula: C22H30N6O4S · C6H8O7
  • Molecular weight: base: 474.6 – salt: 666.7 g/mol